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Does naltrexone help with weight loss? Naltrexone, an opiate antagonist, and bupropion, a noradrenergic/dopaminergic antidepressant, have many effects on the reward systems of the brain. However, only bupropion induces weight loss in obese individuals, while naltrexone does not have any appreciable effect.
Does naltrexone help with chronic pain? Naltrexone is a medication that has been used for many years to treat opioid addiction. When given at a smaller dose (usually 4.5mg), the drug may help to reduce pain associated with inflammatory and autoimmune conditions, such as multiple sclerosis and Crohn's disease.
What is the half life of naltrexone? The mean elimination half - life (T-ВЅ) values for naltrexone and 6-ОІ-naltrexol are 4 hours and 13 hours, respectively. Naltrexone and 6-ОІ-naltrexol are dose proportional in terms of AUC and Cmax over the range of 50 to 200 mg and do not accumulate after 100 mg daily doses.
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